Skip to main content

Revision guide · IGCSE

IGCSE Biology: aerobic and anaerobic respiration

Respiration is the set of chemical reactions in cells that break down nutrient molecules, usually glucose, to release energy. Aerobic respiration uses oxygen: glucose + oxygen -> carbon dioxide + water (balanced: C6H12O6 + 6O2 -> 6CO2 + 6H2O). Anaerobic respiration releases much less energy per glucose and needs no oxygen: in muscles glucose -> lactic acid; in yeast and plants glucose -> ethanol (alcohol) + carbon dioxide. Cambridge 0610 adds the uses of energy, oxygen debt and how it is removed; Edexcel 4BI1 adds ATP as the energy carrier and the respiring seeds practical. Respiration is not breathing, and that distinction alone saves marks.

Facts checked:

At a glance

Cambridge section
0610 topic 12 (12.1 to 12.3)
Edexcel section
4BI1 statements 2.34 to 2.39
Aerobic (balanced)
C6H12O6 + 6O2 -> 6CO2 + 6H2O
Yeast (balanced, Cambridge Supplement)
C6H12O6 -> 2C2H5OH + 2CO2
Where
Aerobic respiration mainly in mitochondria

Aerobic and anaerobic respiration compared

FeatureAerobicAnaerobic (muscles)Anaerobic (yeast, plants)
Oxygen neededYesNoNo
ProductsCarbon dioxide and waterLactic acidEthanol and carbon dioxide
Energy released per glucoseMuch moreMuch lessMuch less
When it happensAll the time in most cellsVigorous exercise when oxygen supply cannot keep upYeast in low oxygen; plant roots in waterlogged soil
Use to peopleBread making (carbon dioxide), brewing (ethanol)

Glucose is only partly broken down in anaerobic respiration, which is why less energy is released.

Key ideas board by board

Cambridge 0610 begins with the uses of energy (12.1.1): muscle contraction, protein synthesis, cell division, active transport, growth, the passage of nerve impulses and keeping a constant body temperature. Core candidates give the word equations; Supplement candidates add the balanced equations for aerobic respiration and for anaerobic respiration in yeast, and explain how the oxygen debt is removed after exercise: the heart rate stays fast to carry lactic acid in the blood to the liver, breathing stays deep and fast to supply oxygen, and the liver respires the lactic acid aerobically.

Edexcel 4BI1 states that respiration produces ATP and that ATP provides energy for cells (2.34, 2.35). Students compare aerobic and anaerobic respiration, give the word and balanced equations for aerobic respiration, and the word equations for anaerobic respiration in plants and animals. The required practical (2.39) shows carbon dioxide and heat released by respiring seeds or other organisms. Edexcel also lists yeast practicals under biotechnology (5.6).

Cambridge Core 12.1.2 asks students to investigate the effect of temperature on respiration in yeast, usually by measuring the gas produced.

Worked example: rate of respiration in yeast

Yeast in sugar solution produces 12 cm^3 of carbon dioxide in 5 minutes at 25 °C and 30 cm^3 in 5 minutes at 35 °C. Rate at 25 °C = 12 ÷ 5 = 2.4 cm^3 per minute. Rate at 35 °C = 30 ÷ 5 = 6.0 cm^3 per minute.

Percentage increase = (6.0 - 2.4) / 2.4 x 100 = 150%. Explanation: the enzymes controlling respiration have more kinetic energy at 35 °C, so there are more frequent effective collisions with substrate. At much higher temperatures, the enzymes denature and the rate falls.

Germinating seeds practical: a flask of germinating seeds and a control flask of boiled (dead) seeds, both rinsed in disinfectant to kill microorganisms, each with a thermometer and plugged with cotton wool. The live seeds warm up; the dead seeds do not. Limewater or hydrogencarbonate indicator shows carbon dioxide released.

Common mistakes

  • Confusing respiration with breathing (ventilation). Breathing moves air; respiration is a chemical reaction in every living cell.
  • Writing that respiration "produces" or "creates" energy. It releases energy.
  • Saying plants only respire at night.
  • Putting carbon dioxide in the muscle anaerobic equation. Lactic acid is the only product.
  • Writing oxygen debt as "lack of oxygen". It is the extra oxygen needed after exercise to break down the lactic acid.
  • Forgetting the control flask, or not killing microorganisms on the seeds, in the heat practical.

Exam technique

Equations are easy marks. Write the reactants and products in words, then symbols, and check the atoms balance: C6H12O6 + 6O2 -> 6CO2 + 6H2O has 6 carbon, 12 hydrogen and 18 oxygen atoms on each side. For "explain why muscles get tired" questions, chain the points: oxygen cannot be supplied fast enough, so anaerobic respiration takes place, lactic acid builds up, causing fatigue and an oxygen debt.

When data compares two organisms or temperatures, quote numbers with units and calculate a difference or percentage if it helps the comparison. Examiners reward the processed figure, not just the raw readings.

How one-to-one lessons help

Respiration overlaps with enzymes, photosynthesis, breathing and exercise physiology, so students often blur the boundaries. A tutor separates the ideas with short diagnostic questions, drills the equations until they are automatic, and works through practical data questions on the whiteboard, marking against real mark schemes from the student's board.

Self-check

  1. Give the word and balanced equations for aerobic respiration.
  2. Give the word equations for anaerobic respiration in muscles and in yeast.
  3. List five uses of energy in the body.
  4. Explain oxygen debt and how it is removed.
  5. Describe a practical showing heat released by respiring seeds, with a control.
  6. Calculate a rate and a percentage change from gas volumes.

Common questions

Is ATP on the Cambridge syllabus?

The Cambridge 0610 respiration statements do not name ATP; they describe respiration as releasing energy. Edexcel 4BI1 statements 2.34 and 2.35 do require ATP.

Do I need the balanced equation for anaerobic respiration?

Cambridge Supplement candidates need C6H12O6 -> 2C2H5OH + 2CO2 for yeast. Edexcel requires only word equations for anaerobic respiration.

Is anaerobic respiration in plants the same as in yeast?

Yes for IGCSE purposes: glucose -> ethanol + carbon dioxide. Edexcel asks for anaerobic respiration in plants and in animals.

How much do LiveTutor biology lessons cost?

$15 a lesson, with a weekly plan of 1 to 5 lessons billed monthly. Lessons are one to one, 60 minutes, online, and the first lesson is free.

Why does respiration release less energy without oxygen?

Glucose is only partly broken down. Much of its chemical energy stays in the lactic acid or ethanol.

Sources

Dates and figures on this page come from these official and published sources. Always confirm deadlines on the official page before acting on them.